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Dna damage following combination of radiation with the bioreductive drug aq4n: possible selective toxicity to oxic and hypoxic tumour cells

While the IL-22/STAT3 pathway primarily promotes de-differentiation in keratinocytes, IFN-/STAT1-3 signaling induces pronounced inflammation, despite exerting antiproliferative effects on these cells

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Among long-term survivors, a major concern is the sequelae induced by treatment including endocrinologic, neurocognitive and behavioral dysfunction

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